Choline Acetyltransferase Administration Decrease Blood Pressure in a Murine Model of Hypertension
نویسندگان
چکیده
منابع مشابه
Blood pressure response in rats to intracisternal administration of choline.
Central administration of acetylcholine or nicotine to rats induces changes in blood pressure and heart rate via central chol inoceptor activation (1, 2). Physostigmine a cholinesterase inhibitor also modifies blood pressure and heart rate (3, 4). Thus, central cholinergic mechanisms may be physio logically involved in the central control of cardiovascular function. In the present experiments, ...
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The localization, purification, and some enzymatic properties of choline acetyltransferase from rat brain were studied. Most assays were performed with a specific radiometric micromethod. Solubilization of the enzyme was examined after homogenization of cerebral cortices by means which disintegrate nerve endings. In isotonic KC1 the enzyme was recovered in solution. In more dilute KC1 the enzym...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2021
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.2021.35.s1.04623